Evoked membrane potential change in rat optic nerve fiber: Computer simulation
نویسندگان
چکیده
منابع مشابه
Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination.
The visual evoked potential (VEP) recording is widely used in clinical practice to assess the severity of optic neuritis in its acute phase, and to monitor the disease course in the follow-up period. Changes in the VEP parameters closely correlate with pathological damage in the optic nerve. This protocol provides a detailed description about the rodent model of optic nerve microinjection, in w...
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A study was made with intra-operative flash--visual evoked potentials (VEP) monitored using a fibre-optic/contact lens photo stimulator in 57 patients undergoing intra-orbital surgical procedures with potential risk to the optic nerve. The VEPs recorded under enflurane and nitrous oxide anaesthesia did not differ significantly in latency or amplitude from the pre-operative recordings. Transient...
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Five patients with optic neuropathy, four vascular and one demyelinating, are described who each complained of an unusual symptom. Bright flashes of light (phosphenes) occurred in the affected eyes and were evoked by sudden unexpected sounds. Movement of the eye alone did not reproduce the symptom. In all patients the phenomenon was sufficiently prominent to interfere with sleep and was the mai...
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A computer simulation of membrane potential generation is presented. It allows the user to vary the intra and extracellular concentrations of sodium, potassium and chloride ions (Na+, K+ and Cl-), and determine the membrane potential and the equilibrium potential for each ion. The permeability coefficients for the ionic species considered, and the temperature may also be changed at will. Concen...
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ERG and VEP responses to counterphase checkerboard stimuli were obtained from cynomolgus monkeys with monocular glaucoma induced by laser photocoagulation of the trabecular meshwork. The glaucomatous eyes showed reductions of PERG amplitude that were directly related to the histologically defined nerve damage. VEP amplitudes were also reduced in the glaucomatous eyes, but were more variable and...
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ژورنال
عنوان ژورنال: Neuroscience Bulletin
سال: 2007
ISSN: 1673-7067,1995-8218
DOI: 10.1007/s12264-007-0052-8